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pentobarbital will lower the level or outcome of alosetron by impacting hepatic enzyme CYP2C9/10 metabolism. Minimal/Significance Unknown.pentobarbital decreases amounts of elvitegravir/cobicistat/emtricitabine/tenofovir DF by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Might result in lack of virologic reaction and doab